4 Best Nike Flyknit Running Shoes in 2022

Jens Jakob Andersen
Jens Jakob Andersen on
4 Best Nike Flyknit Running Shoes in 2022

Introduced in 2012, the Nike Flyknit running shoes revolutionized the world of running. Its state-of-the-art integral knitting technique was something that was never seen before. It was truly innovative creating a one-piece breathable upper, engineered for precision fit and a second-skin feel for runners.

From blistering 5Ks to marathons, or simply for daily jogs or lifestyle use, you can’t go wrong with a pair of Nike Flyknit running shoes. There are more than a dozen of amazing Flyknit models to choose from. To help you save time in choosing the right one, we’ve tested, reviewed, and ranked all of them.

Go ahead and check which particular model really suits your training, racing, or lifestyle needs.

How we test running shoes

To select our top picks for different categories, we analyzed all data from mechanical tests inside our independent shoe lab, reviewed the extensive feedback from our team of wear-testers, as well as used our own knowledge and experience in running and running shoes.

For this particular list, we’ve highlighted the best of the best based on the following process:

  • We buy all the Nike Flyknit running shoes with our own funds to avoid any brand loyalty and bias.
  • We perform a battery of tests in the lab, which involves cutting the shoes into pieces.
  • We weigh and measure over 30 parameters of each model, checking and re-checking the breathability and durability of the Flyknit upper, the softness of the midsole, and many more.
  • Our wear-testers clock in at least 30-40 miles on average for each pair in various training and racing environments.
  • We also collect additional information from other shoe experts and feedback from regular runners.

To get the overall rating, we go to our CoreScore system to punch the numbers based on the gathered data above. Ranging from 0 to 100, the final score is assigned to each model showing which one is really the best option in a category.

Best Nike Flyknit running shoes overall

Nike ZoomX Invincible Run
Nike ZoomX Invincible Run


4.5 / 5 from 432 users
90 / 100 from 28 experts


  • Super-cushioned
  • Insanely fun and bouncy ride
  • Great grip
  • Impressive foot lockdown
  • Stretchy toebox
  • Good for wider feet
  • Not weighing you down
  • Really breathable


  • Unstable on uneven terrain
  • Really tall
  • Break-in period needed


Now, this is what we call FUN! The Nike ZoomX Invincible Run literally made us feel like each step was made of springs. It's NOT going to pace you, but it will make your runs lively and effortless! If you want a premium daily trainer that's going to work best on long, easy days on the road, we tell you, this is THE best of its kind.
See our full review and facts

Best value Nike Flyknit running shoes

Nike React Infinity Run Flyknit 2
Nike React Infinity Run Flyknit 2


4.3 / 5 from 2,024 users
88 / 100 from 18 experts


  • Exceptional flywire lacing
  • Soft & cushioned ride
  • Great for heavier runners
  • Incredible grip (road)
  • Very breathable
  • Padded heel collar
  • No heel slipping
  • True to size
  • Durable 


  • Tongue rips apart
  • Lacks pop for tempo runs
  • Slippery on snow and ice


In the Nike React Infinity Run Flyknit 2, our feet just felt locked in place! And even after rough wear testing, this daily trainer proved itself a durable shoe. It's loaded with lots of cushion that's not too soft nor too rigid, making it supportive and ideal for heavy runners. As a daily running shoe, it sticks to what it's designed to do - it's not going to make you run fast, but it does offer a smooth, easy ride.
See our full review and facts

What are the cheapest Nike Flyknit running shoes in 2022?

  1. Nike Joyride Run Flyknit - from £76
  2. Nike React Phantom Run Flyknit 2 - from £80
  3. Nike Free RN Flyknit 2018 - from £88
  4. Nike Zoom Fly 4 - from £103
  5. Nike React Infinity Run Flyknit 3 - from £103
  6. Nike Epic React Flyknit 2 - from £103
  7. Nike ZoomX Invincible Run - from £134

See all Nike Flyknit running shoes sorted by lowest price

Jens Jakob Andersen
Jens Jakob Andersen

Jens Jakob is a fan of short distances with a 5K PR at 15:58 minutes. Based on 35 million race results, he's among the fastest 0.2% runners. Jens Jakob previously owned a running store, when he was also a competitive runner. His work is regularly featured in The New York Times, Washington Post, BBC and the likes as well as peer-reviewed journals. Finally, he has been a guest on +30 podcasts on running.